Protease Inhibitors and Phosphatase Inhibitors
MilliporeSigma™ Calbiochem™ InSolution™ Necrostatin-1
A cell-permeable, potent, and selective blocker of necroptosis (EC50 = 494nM in FADD-deficient Jurkat cells treated with TNF-α), a nonapoptotic necrotic cell death pathway mediated by death-domain receptors (DRs) that offers neuroprotection in a murine model of ischemic brain inj
MilliporeSigma™ Calbiochem™ Calpain-1 Substrate II, Fluorogenic
An internally quenched peptide substrate that is optimized for calpain-1 amino acid recognition motifs at the primed as well as the non-primed sides.
MilliporeSigma™ Calbiochem™ Phosphatase Inhibitor Cocktail Set IV
A cocktail of three phosphatase inhibitors for the inhibition of both serine/threonine and alkaline phosphatases.
Oxymetazoline Hydrochloride, USP, Spectrum™ Chemical
O1359, 2315-02-8, C16H24N2O·HCl
MilliporeSigma™ Calbiochem™ S1P Receptor 2 Agonist, CYM-5520
A potent, selective, allosteric agonist of sphingosine-1-phosphate receptor 2 (S1PR2; EC50 = 480 nM).
MilliporeSigma™ Calbiochem™ DL-threo-PDMP, Hydrochloride
PDMP closely resembles the natural sphingolipid substrate of brain glucosyltransferase and acts as a potent and competitive inhibitor of this enzyme.
MilliporeSigma™ Calbiochem™ Aloisine A
A cell-permeable pyrrolo-pyrazine compound that exerts anti-proliferative effects.
MilliporeSigma™ Calbiochem™ PD 150606
A cell-permeable, non-competitive, selective non-peptide calpain inhibitor [Ki = 210 nM for calpain-1 and 370 nM for calpain-2.
MilliporeSigma™ Calbiochem™ Calpain Substrate IV, Cell-Permeable, Fluorogenic
The non-permeant fluorogenic Calpain Substrate III is made cell-permeable by a c-terminal heptaarginine extension via a Glu linkage.
MilliporeSigma™ Calbiochem™ Gabapentin
A water soluble GABA analog that interacts with voltage-gated calcium channels in cortical neurons.
MilliporeSigma™ Calbiochem™ bpV(phen)
A potent protein phosphotyrosine phosphatase inhibitor and insulin receptor kinase (IRK) activator.
MilliporeSigma™ Calbiochem™ FGF/PDGF/VEGF RTK Inhibitor
The FGF/PDGF/VEGF RTK Inhibitor, also referenced under CAS 144335-37-5, controls the biological activity of FGF/PDGF/VEGF RTK. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
MilliporeSigma™ Calbiochem™ Wnt Antagonist III, Box5
The Wnt Antagonist III, Box5 controls the biological activity of Wnt. This small molecule/inhibitor is primarily used for Cancer applications.
MilliporeSigma™ Calbiochem™ InSolution™ Roscovitine
A potent and selective inhibitor of cyclin-dependent kinases (Cdks)
MilliporeSigma™ Calbiochem™ PRIMA-1
A cell-permeable quinuclidinone analog with antitumor properties.